We aren't aware of this problem, sorry! If you can narrow down when it happens, we would love to fix it!
One thing to keep an eye on is if you turn off Auto Key
and have not changed the draw order, it should show up green:
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If you change the draw order, it should show up orange:
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If you click the key icon to set a key, or have set a key on the current frame, it should show up red:
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If your draw order is changing unexpectedly, it could be a bug with auto keying. When such a bug occurs, you will see the orange key icon when you have not changed the draw order. Note you'll only see this when auto key is off. When it is on, you won't see the orange key because auto key will just key what it incorrectly thinks has changed! Such a bug can wreak havoc and would be our highest priority to fix, we just need to be able to cause it to happen so we can track down the problem to fix it.